We Invest In

Technology that unlocks
human potential
Platforms to discover
breakthrough therapies
Artificial intelligence to
enable human interaction
Technology that connects
people around the world
Software that's built
to protect kids online

What We Do

We believe the world is changing faster than ever.

We are an early-stage venture capital firm investing in transformative companies harnessing information growth and computing power to change the world.

We believe the most important companies of the future will be the product of three forces: the exponentially increasing availability of information; rapid advancements in the science of computing; and the ingenuity of visionary founders.

We have seen the information + computing + people thesis transform the business of investment management, and we support companies applying it to other industries.

Our Values

Our Values


We believe we are stronger as a collective than as individuals, and look for every opportunity to augment our own abilities with the resources and expertise around us.


We are humble enough to acknowledge that which we cannot know or predict, and remain diligently focused on our search for knowledge and understanding.


We endeavor to understand and respect the ambitions and challenges of entrepreneurs, and do all we can to support them as they work to achieve their objectives.


We earnestly challenge the status quo and are ambitious in our efforts to improve upon it through the discovery and creation of technological breakthrough.

Our Focus

We support companies using data science and advanced engineering to create the future.

Early stage

We invest early—from seed to series B—and stick around as a long-term partner.

Across industries

From infrastructure tools and healthcare to real estate and consumer hardware, we support data- and computing-driven transformation in every industry.

Where we have expertise

We bring Two Sigma brainpower in software engineering, data science, quantitative modeling, machine learning and more to all we do.

How We Help

We have deep expertise and an extensive technical network.

Throughout 15+ years of building Two Sigma, we’ve learned a lot about what makes a technology company succeed. Though we can hardly be called a startup anymore, our team and the over 1,600 employees and 200 PhDs we’re lucky to call colleagues bring a wealth of extraordinary experience to every company we work with.

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Our Focus

We have a deep appreciation for the challenges that go into building a startup and use our hard-earned experience in data science, software engineering, and building world-class organizations to give you superpowers.

Data Science

Our network of data science and machine learning experts can help you with everything from evaluating and integrating new data sets, to structuring your data and developing and refining your models.

“Two Sigma Ventures hosted a 2-day competition with 20+ Two Sigma data scientists to help us increase the accuracy of machine learning algorithms by over 30%.”

– Will Ahmed, Founder & CEO, WHOOP

Product & Engineering

From helping you design your tech infrastructure to establishing strong reliability engineering practices, we can give you the extra bandwidth and know-how to get better products to market faster.

“Senior engineers from Two Sigma did a comprehensive review of our architecture, helping identify vulnerabilities and improvements to consider as we scale.”

– Germain Chastel, Co-Founder & CEO, NewtonX

Leadership & Talent Solutions

People are your most important asset. From recruiting and talent management, to organizational design, executive coaching, and values development, we’ll help you evolve your team as your company grows.

“From growing our leadership team to finding our first Head of People, Two Sigma Ventures has armed us with connections as we’ve grown to 150+ employees.”

– Tina Larson, Chief Operating Officer, Recursion

Marketing & Comms

We can be a resource to help you tell your story, from crafting a marketing strategy and developing a communications plan, to helping secure coverage for your most important announcements.

“The team at Two Sigma Ventures helped us land coverage in The New York Times, Business Insider, Reuters, and more, leading to over 50+ qualified leads.”

– Alex Batlin, Founder & CEO, Trustology


Our co-working and event space in downtown NYC is a place for our portfolio companies to work, hold meetings, or host events. Several seed-stage companies use the space as their full-time office. For the rest of the portfolio, the space is a home-base in NYC for drop-ins, meetings and events.

Our Portfolio

We have invested in 50+ companies and growing.

Zymergen uses data, machine learning, automation, and software tools to unlock the power of biology through technology.


CoverWallet is an online platform that offers insurance-management services to its clients.


Enigma takes the mystery out of open-source public data, providing analysis tools that collect, curate, and mine public government information and available research information for insight.


Snapshot of Enigma Program

NS1 is an intelligent domain name system (DNS) and traffic-management platform that uses a data-driven architecture to make routing decisions in real-time.


Snapshot of NS1 program

Placed provides real-world insights to brands and advertisers by measuring and analyzing what its opt-in panel of smartphone customers likes, where they are, and what they like to do.


Snapshot of Placed program

x.ai is an artificial-intelligence-driven personal assistant that combines machine learning and human intelligence to schedule meetings.


Snapshot of Xai Program

Our Team

We are data scientists, engineers, entrepreneurs & operators.

Our core team is dedicated to finding and partnering with great founders. We are supported by Venture Partners who bring years of experience building Two Sigma, and an army of experts from Two Sigma who are eager to share their skills.

Two Sigma staff talking at a whiteboard
Two Sigma staff talking at a whiteboard